Optimal Control of a Fed-Batch Fermentation Involving Multiple Feeds
نویسندگان
چکیده
منابع مشابه
Optimal Control of a Fed-Batch Fermentation Involving Multiple Feeds
A nonlinear dynamical system, in which the feed rates of glycerol and alkali are taken as the control functions, is first proposed to formulate the fed-batch culture of 1,3-propanediol 1,3-PD production. To maximize the 1,3-PD concentration at the terminal time, a constrained optimal control model is then presented. A solution approach is developed to seek the optimal feed rates based on contro...
متن کاملOptimal control of fed-batch fermentation involving multiple feeds using Differential Evolution
Differential Evolution (DE), an exceptionally simple and robust evolutionary algorithm with Lagrangian like method, was used for solving optimal control and parameter selection problems of fed-batch fermentation involving general constraints on state variables. These infinite dimensional optimization problems were approximated into the finite dimensional optimization problems by control vector ...
متن کاملOptimal switching control of a fed-batch fermentation process
Considering the hybrid nature in fed-batch culture of glycerol biconversion to 1,3-propanediol (1,3-PD) by Klebsiella pneumoniae, we propose a state-based switching dynamical system to describe the fermentation process. To maximize the concentration of 1,3-PD at the terminal time, an optimal switching control model subject to our proposed switching system and constraints of continuous state ine...
متن کاملOptimal Adaptive Control of Fed-batch Fermentation Processes
This paper presents a unifying methodology for optimization of biotechnological processes, namely optimal adaptive control, which combines the advantages of both the optimal control and the adaptive control approaches. As an example, the design of a substrate feeding rate controller for a class of biotechnologlcal processes in stirred tank reactors characterized by a decoupling between biomass ...
متن کاملOptimal Feed Rate Control of Escherichia coli Fed- batch Fermentation
Abstract: In this paper an optimal control algorithm for E. coli fed-batch fermentation has been developed. A simple material balance model is used to describe the E. coli fermentation process. The optimal feed rate control of a primary metabolite process is studied and a biomass production is used as an example. An optimization of a fed-batch fermentation process is usually done using the calc...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Applied Mathematics
سال: 2012
ISSN: 1110-757X,1687-0042
DOI: 10.1155/2012/245315